The First Descendant: Enzo Build & Best Loadout – Season 4 E1

Welcome to The First Descendant Enzo Build Guide for Season 4 Episode 1.

In this guide, we will explain how to create a powerful build for the Enzo Descendant. We’ll cover how the skills work and which weapons, stats and modules you need to create the most powerful build for Enzo.

Table of Contents:

1. How to play Enzo
2. Enzo Builds Overview – Modules
   1. Enzo Ammo Support Build
   2. Enzo Focus Fire DPS Build
3. Enzo Trigger Module
4. Enzo Ancestor Modules
5. Arche Tuning for Enzo
6. Enzo Equipment Overview
   1. Best Weapons for Enzo
   2. Best Reactor for Enzo
   3. Best External Components for Enzo
   4. Inversion Reinforcements
   5. How To Farm Enzo Modules
7. Enzo Basics
   1. How to unlock Enzo
   2. All Enzo Skills
   3. All Enzo Transcendent Modules
   4. Best Grapple Hook for Enzo
8. Enzo’s Story

For builds on other Descendants, visit our The First Descendant Builds Database, or check out the Character Tier List or the Weapon Tier List. 

TFD Wiki: We have expanded Alcasthq with tfd.gameslantern.com, a Wiki & Database for anything related to The First Descendant. Use the Character Editor or the Weapon Editor to theorycraft and create builds yourself. Browse Descendants, Weapons, Leaderboard Loadouts or use the Compare Tool. There are plenty of other features you can check out, too!

Here is a quick list of the strengths and weaknesses of the Enzo Build for The First Descendant.

How to Play Enzo in the First Descendant

Enzo is a very useful Descendant. You can play him both as support character to buff allies (unlimited ammo, faster speed) or as DPS character. We will explore both options on this page. Learn about his skills in detail in the Enzo’s Skill Explanation section. Enzo’s Transcendent Modules are also exceptional!

Enzo is a weapon-based Descendant and therefore relies on a maxed-out weapon to be effective!

Enzo’s Support Build

Enzo’s Support Build focuses on providing allies and yourself with unlimited ammo and faster movement speed. Having unlimited ammo is especially useful on heavy armor-type weapons such as rocket launchers. With this, you can infinitely spam rockets! Additionally, we are also built tanky to mitigate incoming damage.

• Check out the Enzo’s Support Build to find out how to set it up.

Enzo’s Focus Fire DPS Build

Enzo can also be played as a DPS character. This will require you to have a maxed-out weapon! With this setup we have the 60% faster reload speed, infinite ammo, and higher weapon crit rate. This works flawlessly with a Rocket launcher or Shotgun. Additionally, our turret also deals nice damage and scales with shield size. Therefore, we max out our shield and put our HP at 1.

• Check out the Enzo Focus Fire DPS Build to see how this exactly works.

Enzo’s Equipment: Make Or Break It!

To unlock Enzo’s full potential, you need the right Weapons, Reactors, and External Components:

• Modules: Selecting the right Modules boosts your character’s power the most; this is very important and changes depending on what build you use.
• Ancestor Modules: Having a good Ancestor module with the right perks is key to maxing out your damage potential.
• Weapons: You need to have a maxed-out weapon for Enzo to be effective. See the Best Weapons for Enzo section.
• Reactors: Selecting the right reactor stats can drastically improve the build. Check out the Best Reactors for Enzo section.
• External Components: These are critical for survivability. Properly configured, they double or triple your HP and DEF. Learn more in the Best External Components for Enzo section.

Building a top-tier The First Descendant Enzo Build requires not only the right modules but also optimized weapons, reactors, and components.

Best Enzo Builds Overview for The First Descendant

 

• Crystallization Catalysts: To unlock the necessary socket slots.
• Energy Activator: To increase overall module capacity.
• Gold & Kuiper: Best Gold Farming Method – Best Kuiper Shard Farming Method.

Equipment: I will cover Weapons, Reactors, External Components, Inversion Reinforcements, and Transcendent Modules in the Enzo Equipment section. To maximize the power of any build, you must get the correct items!

Enzo Support Build

• Enzo Support Build Type: Group Build, only effective if paired with other weapon-based Descendants.
• Enzo Support Build Focus: Support group for infinite ammo and other buffs.

This Enzo Support Build works best if paired with other weapon-based Descendants. Enzo supports every group member with infinite ammo because of how the setup is built. We are using the Supply Tactical Armor module that buffs movement speed and reduces incoming damage. This is very useful if you want to clear content fast.

Enzo Support Build Module Configuration Table

Module Slot	Module Name	Mod Level	Socket Type	Crystallized
0 (Trigger Module)	Full Arche Jacket	N/A	N/A	N/A
1 (Skill Module)	Supply Tactical Armor	Max	Malachite	No
2	Increased HP	Max	Cerulean	Yes
3	Battle of Stamina	Max	Cerulean	Yes
4	Nimble Fingers	Max	Malachite	Yes
5	Maximize Range	Max	Rutile	Yes
6	MP Conversion	Base	Malachite	Yes
7 (Sub Module)	Mid-Air Maneuvering	Max	Malachite	Yes
8	Maximize Conservation	Max	Malachite	Yes
9	Skill Extension	Max	Rutile	Yes
10	Skill Expansion	Max	Rutile	Yes
11	Maximize Duration	Max	Rutile	Yes
12	Heat Release (Flex)	Max	Almandine	Yes

Enzo Focus Fire DPS Build

• Enzo DPS Build Type: Used for Solo DPSing.
• Enzo DPS Build Focus: Can be used for any content mobbing or bossing.

This Enzo Focus Fire DPS Build focuses on dealing as much damage as possible. You will need a maxed-out weapon for this to be effective. With this setup, you will have infinite ammo, 60% faster reload speed, and a strong Turret that will help you kill anything.

Additionally, we will only have 1HP but have an insane shield size. This is also because we get stronger the more shield size we have.

Important: You need to activate your first skill to get the 60% reload speed and then activate your turret. 

Enzo DPS Build Module Configuration Table

Module Slot	Module Name	Mod Level	Socket Type	Crystallized
0 (Trigger Module)	Full Arche Jacket	N/A	N/A	N/A
1 (Skill Module)	Focus Fire	Max	Xantic	No
2	Increased HP	Max	Cerulean	Yes
3	Stim Accelerant	Max	Cerulean	Yes
4	Nimble Fingers	Max	Malachite	Yes
5	Amplification Control	Max	Rutile	Yes
6	MP Conversion	Base	Malachite	Yes
7 (Sub Module)	Mid-Air Maneuvering	Max	Malachite	Yes
8	Maximize Conservation	Max	Malachite	Yes
9	Overwhelming Shield	Max	Cerulean	Yes
10	HP Conversion (Shield)	Max	Cerulean	Yes
11	Maximize Duration	Max	Rutile	Yes
12	Increased Shield	Max	Cerulean	Yes

Enzo Trigger Module

You need to first unlock the trigger module slot for each character. Learn how to unlock Trigger Modules in The First Descendant.

• Mobbing & Support: Full Arche Jacket

Enzo Ancestor Module

Ancestor Modules can be slotted once you have acquired them. However, they are only worth it once you have an Ancestor module with good stat rolls on them.

• Enzo Ancestor Module: Quartermaster’s Resolution
• Superconductive Cooling Units (Needed to Reroll perks): How to farm
• Must Read: How Ancestor Modules Scale & Examples

It is only worth slotting an Ancestor Module if you have good rolls on it; otherwise, it isn’t worth it.

• Ideal Positive Rolls
  • Non-Attribute
  • Singular
  • Cooldown
  • Duration
  • Range
• Ideal Negative Rolls
  • Skill Modifier
  • Dimension/Singular Skill Boost (Whatever you don’t use in Support vs Mobbing)

Ancestor Module: What to Replace and Why

To slot an Ancestor Module effectively, identify existing modules that share the same primary stat. By replacing a standard module with an Ancestor version that offers similar values, you maintain your core build while gaining its additional unique perks as a ‘free’ bonus.

• How to: Replace a standard module with an Ancestor Module that mirrors its main perk.
  • The values should be close; you preferably don’t want to replace a 100% with a 30% value.
• Example 1: If your Ancestor Module provides Skill Critical Hit Rate, replace Skill Insight.
• Example 2: If your Ancestor Module provides Max HP, replace Increased HP.
• Example 3: If your Ancestor Module provides Skill Effect Range, replace Skill Expansion.
• Result: All other perks from the Ancestor Module will basically be a “freebie” and improve your build!
• Helpful Links:
  • Descendant Synchronization Value Explained
  • Ancestor Module Image & Build Examples
  • Ancestor Module Perk Quality & Stat Scaling Explained

As long as the Ancestor Module reaches a similar value to the one you’re removing, every additional stat on that Ancestor Module becomes a “free” bonus for your build.

Arche Tuning for Enzo

• Image 1: Arche Tuning for Enzo’s Support Build
• Image 2: Arche Tuning for Enzo’s DPS Build

The Arche Tuning System in The First Descendant is important for every Character; it buffs your stats by a good amount. F

You level up Arche Tuning in the Sigma Sector Dropoff Operation. Mutant Cells also drop there with a small chance.

Enzo Equipment Overview in The First Descendant

Equipment is the cornerstone of any successful The First Descendant Build. For Enzo, having the right setup can mean the difference between dominating content and falling short. This section breaks down the essential equipment types: Weapons, Reactors, External Components, and Transcendent Modules, and explains how they maximize his power.

Equipment Type	Importance	Key Benefits
Weapons	Critical for maximizing damage. Enzo relies on maxed-out weapons.	Increases overall DPS. Skills amplify the effect of the weapons Enzo use. Proper weapon selection can double or triple damage.
Reactors	Essential for boosting skill performance. Enzo only needs skill cooldown and duration perks.	Enhances skill potency. Ensures Enzo’s abilities perform at peak levels.
External Components	Arguably the most impactful equipment. Dramatically improves survivability and utility. Set Buffs with 2/4 pieces.	Quadruples stats like HP or DEF. Adds utility like MP recovery. Enables effective performance in high-difficulty content. Core System Enhancements.
Inversion Reinforcements	Adds further buffs to your build.	Perks that can make a difference in build power.

Best Weapon for the Enzo Build in The First Descendant

Depending on what content you do with Enzo, you will need different weapons. Below you can find the Top 3 Weapons for Enzo in The First Descendant.

Note: You can just run around with the Restored Relic for any content and you will be set. So I would focus on building out this weapon first and then go build others.

Top Weapons for Enzo

Top Weapons for Enzo

Weapon	Category	Key Features	Why It’s Great for Enzo
ATR-0 Prototype	570	Non-Attribute Skill Power Amplification Rate Stat Stick	Boosts all skill damage.
Restored Relic	Launcher	Guided Rounds Cluster Bombs	This is a powerful rocket launcher that fires guided rounds that explode into clusters to hit even more enemies! Pair this with Enzo’s infinite ammo, fast reload speed and everything dies. You won’t even really have to aim because the weapon has homing missiles. Can be used for single-target and AOE damage.
Malevolent	Hand Cannon	Strong AoE damage	One of the most powerful AoE weapons. Infinite ammo with Enzo and super fast reload.
Last Dagger	Hand Gun	High Burst Single Target DPS. Insane Fire Rate	Currently, one of the most powerful ST weapons. Fast fire rate to nuke targets.

Other Useful Weapons

Other Useful Weapon Options for Enzo

Weapon	Category	Key Features	Why It’s Great for Enzo
Exterminator	Rocket Launcher	Easily destroys enemy Assault Ships. Easily destroys enemy Swarm Sacks & Tunnels. Auto Target function when aiming.	Weapon specialized in destroying Assault Ships, Swarm Sacks & Tunnels.
Shadow	Sword	Massive AoE & ST damage. Strong Special AoE skill.	Best allrounder Sword for massive damage. Fast movement.
Thunder Cage	Submachine Gun	Everyone has this weapon from the main story (easily accessible). “Newbies’ Best Friend” Rains down thunder on enemies.	Deals great AoE damage. Overall good performance.

Best Reactor for Enzo in The First Descendant

Selecting the best reactor for Enzo in The First Descendant can significantly enhance his abilities, allowing you to maximize his effectiveness in various scenarios. Not only does the reactor determine your skill damage, but it also gives additional secondary benefits through modifiers.

For Enzo, the type of reactor doesn’t matter because he relies on weapons to deal damage. Only the modifiers are important! We want Skill Cooldown and Skill Duration.

How to find the Location of Reactors

Reactor drop locations change every day. Not many players know this and get confused. Now, there is a reactor search function in-game. Go to the map and press on Difficulty Level Rewards. In here, you can see where all the reactors currently drop.

Note: It is possible that not all reactor types are currently dropping. You have to come back and recheck every day.

If your specified reactor drops in an area, you go there and farm any missions and monsters (Preferably missions with lots of monster spawns). There will be plenty of reactors dropping from monsters all over the place, any monster works. It will take a while to get a good reactor!

Best External Components for the Enzo Build

Here is the best External Components setup for both Enzo Builds that you can use.

Additionally, External Components now also have core slots; it is recommended to slot Max HP and DEF cores.

Firebrand + Hunter Set Combo for Enzo – Support Build

Enzo External Components Support Build

External Component Part	Base Stat	Selective Best Stats	Cores
Fire Brand Auxiliary Power	Max HP	Max HP MP Recovery Out of Combat	Max HP DEF
Hunter Sensor	DEF	Max MP MP Recovery in Combat	Max HP DEF
Fire Brand Memory	Max Shield	MP Recovery Modifier DEF	Max HP DEF
Hunter Processor	Max HP	Max Shield Shield Recovery Modifier	Max HP DEF

Shell + Ascending Armory Set Combo for Enzo DPS Build

Enzo External Components DPS Build

External Component Part	Base Stat	Selective Best Stats	Cores
Ascending Armory Auxiliary Power	Max HP	Max HP MP Recovery Out of Combat	Max HP DEF
Ascending Armory Sensor	Max HP	Max MP MP Recovery in Combat	Max HP DEF
Shell Crusher Memory	Max HP	MP Recovery Modifier DEF	Max HP DEF
Shell Crusher Processor	Max HP	Max Shield Shield Recovery Modifier	Max HP DEF

Inversion Reinforcements Setup for Enzo

You can find the Inversion Reinforcements in the inventory, located on the bottom left side. This changes with every new season and needs to be leveled up again.

At max level, you have unlocked everything. While the last perk is always active in each row, you can only slot three additional perks at the bottom. Here is what you want to prioritize:

• Skill: Perk 1.
• Weapon: None.
• Recovery: Perk 1.
• Survival: Perk 2.
• Season: None.

How To Farm Enzo Modules

Farming Enzo’s Transcendent Modules can be an absolutely painful experience. However, even though it still feels awful to farm them, it actually used to be even worse. You will have to open so-called Encrypted Vaults that are placed all over the map. To open these, you need Code Breakers/Analyzers. Enzo specializes in opening these, it is pretty much impossible to do this with any other character. Enzo has way more time and leeway while playing the minigame.

1. The Mods only drop on Precise Encrypted Vaults (Blue) and Ultraprecise Encrypted Vaults (Purple)
2. Vaults can be seen if you are on the map by these icons (image 2 above).
3. You need Code Analyzers (normal) and Code Breakers (hard) to open the vaults.
4. Best way to farm Code Analyzers and Breakers is by simply playing the game, they can drop from any monster (low drop chance). Or you can farm a high monster density mission like Anticipated Ambush Point mission on hard.
5. Special Operations (Spawn in Albion, walk forward and then left, the yellow orb terminal) also drop them.

Enzo Transcendent Module Locations:

• Focus Fire: Any Fortress zone (normal/hard)
• Reinforce Front Line: Any Echo Swamp & Hagios zone (normal/hard)
• Supply Firearm Enhancer: Any Vespers & White-night Gulch zone (normal/hard)
• Supply Tactical Armor: Any Sterile Land & Agna Desert zone (normal/hard)
• Tip: Sometimes, Events reward you with Transcendent Module Selection boxes that can also include Enzo mods!

Enzo Basics in The First Descendant

If it is your first time playing Enzo in The First Descendant, here are some useful things you should know.

1. How to unlock Enzo
2. All Enzo Skills
3. All Enzo Transcendent Modules
4. Best Grapple Hook for Enzo

How to Get Enzo in The First Descendant

Let’s take a quick look at how to unlock Enzo in the First Descendant. To unlock Enzo, you have to purchase him from the store, or research him. You need the following items to research Enzo:

• 1x Enzo Enhanced Cells
  • Archive Shards
• 1x Enzo Stabilizer
  • Archive Shards
• 1x Enzo Spiral Catalyst
  • Archive Shards
• 1x Enzo Code
  • Archive Shards
• 400k Credits

When you visit Magisters Anais at the Research Institute you can hover over each item. Then click on Acquisition Info and it will tell you where this specific item drops. You can view an in-depth guide here on How to unlock Enzo in The First Descendant.

The First Descendant Enzo Skills Explained

In this section, we are going to explain the skills available to our Enzo Build in the First Descendant, how each skill works and the best ways for you to use them.

Icon	Skill Name	Description
	Start Supply	Summons a Bullet Supplying Device at the designated location. Supplies bullets to allies that approach the Device. The Bullet Supplying Device can be used once by each ally, and disappears when everyone has used it or its duration ends
	Explosive Drone	Launches an Explosive Drone forward. The Explosive Drone explodes on contact with an enemy or a terrain object, dealing damage.
	Enhance Combat Suit	Summons a Shield Recovery Comms. When the Shield Recovery Comms is first summoned, recovers Enzo’s Energy Shield by a certain amount, then continues to recover the Energy Shield through Enhance Combat Suit effect.
	Perfect Support	Summons a Small Supply Ship to himself and his allies. The Small Supply Ship periodically provides Supply Bullets and grants Perfect Support to allies. The Small Supply Ship attacks enemies in front while it is active, and when the skill ends, it fires a missile forward that causes a big explosion at its destination.
	Fire Support (Passive)	Grants Fire Support to allies within an area around Enzo, increasing their max ammo capacity. This efficiency of this effect increases marginally with the number of Enzos in the squad. Efficiency increases when Enzo disarms the security of the Encrypted Vault, and rewards increase when this happens.

Start Supply

Explosive Drone

Enhance Combat Suit

Perfect Support

Fire Support (Passive)

All Enzo Transcendent Modules Explained

First, let us look at the full list of all Transcendent Modules for Enzo in The First Descendant. It is important to note that not all of the modules will be used. Some are more effective than others!

Module Name	Module Description	Best In Slot
Reinforce Front Line	Spawns a Front Line Reinforcement Device that grants a Firearm ATK Up to allies in range.	Not Used
Focus Fire	Attaches a Combat Drone to himself. On Firearm Critical Hit attack, increases the drone’s duration. Increases the Max Stack of Explosive Drone.	Enzo DPS Build
Supply Tactical Armor	Whenever Enzo buffs an ally, he grants himself and all allies Incoming Damage DOWN and Movement Speed UP.	Enzo Support Build
Supply Firearm Enhancer	Summons a Firearm Enhancement Device. Touching the device grants Weak Point Damage and Firearm Critical Hit Rate Up.	Not Used

Smooth Grapple Hook for your Enzo Build

Using the standard Grapple Hook in The First Descendant can be a pain, and it feels kinda frustrating at times. Don’t worry, there is a way better alternative that will make it a joy to use the grappling hook!

It is called the Mid-Air Maneuvering Sub Module. I use this on all my The First Descendant Builds because it improves grappling by so much.

With this Module, you can attach your Grapple Hook to anything, even air! That means you can simply aim towards the sky and Hook up your grapple hook there for guaranteed fast movement!

Here is a guide on how to get the Mid-Air Maneuvering Sub Module in The First Descendant. It won’t take a lot of effort, but it will improve your build and overall gameplay in The First Descendant.

Enzo’s Story in The First Descendant

If asked to pick the most important factors for winning a war, the general response would be powerful weapons, a strong fighting force, and cutting-edge technology. However, The First Descendant Enzo would beg to differ.

Powerful weapons must be transported to the front lines on time, and a strong fighting force must be well-fed and capable of shooting accurately. Also, cutting-edge technology demands sufficient resources to sustain mass production. As such, for Enzo, the most important factor in winning a war is a seamless and systematic supply flow. If only such things had been achievable at that time… Enzo continues to blame himself for what had happened to his cousin, Lepic, as well as the annihilation of the 44th Grenadier Squad.

In the past, during the Agna Desert Defense Operation, Enzo, who had been quartermaster at the time, drove towards the front lines in a tactical armored vehicle to deliver the much needed ammunition to the besieged 44th Grenadier Squad.

Not only did he intend to rescue his sole surviving blood relative, Lepic, but it was a race against the clock, as the timely supply of ammunition could turn the tide of battle.

But perhaps he was too hasty. The Supply Squad, which was enroute without a proper escort, was ambushed by the Vulgus, and all of the ammunition they were carrying was lost in the ensuing explosion. Now, it was he, not the 44th Grenadier Squad, who was in danger of losing his life. Despite finding himself facing death, he instead despaired at the fact that he had lost the ammunition which he needed to deliver to his teammates. That feeling of hopelessness… Losing both his comrades and his cousin this way…

At that moment, supplies started to appear from the ground on where he had been crying out in despair. It was later revealed that this phenomenon had been caused by Enzo’s Arche ability, Inorganic Matter Spatial Awareness Summoning, and this ammunition had been summoned from a faraway Albion ammunition depot. However, Enzo, who was unaware of this fact, believed that a miracle had happened and defeated the enemies by himself, eventually succeeding in transporting the supplies to the 44th Grenadier Squad’s location.

However, there would be no second miracle. By the time he arrived, the Grenadier Squad had been wiped out, and Lepic, who was lucky enough to survive, had lost his right arm. Although Lepic would overcome adversity and become an outstanding Descendant, Enzo blamed himself, believing that if there had been no issues with the supply flow, a loss of this scale could have been prevented in the first place.

Never again would he allow himself to fail. Through perfect supply operations, he would save his comrades and win the war. Even now, as a Descendant under the direct command of Albion HQ, and as an executive officer, he is always revisiting the events of that day, repeating his promise. And whenever there is place that requires assistance, he will go in person to the front, providing as many supplies as the soldiers needed. His aim? To make something as essential for victory as supplies be considered a given and not a miracle.

Related Guides for The First Descendant

You can also check out our Ultimate Weapons Database for The First Descendant or the Builds Database for The First Descendant.